The referring doctor had suggested a diagnosis of eruption. Auclair pj, cuenin p, kratochvil fj, slater lj, ellis gl. Intralesional steroid treatment of central giant cell. A central giant cell granuloma in posterior part of maxillaa case. Central giant cell granuloma was 1st described in jaws by jaffe 1953. The central giant cell granuloma, also known as cgcl or giant cell lesion, was first described by jaffe in 1953.
Central giant cell granuloma venkateshwarlu et, al 6. Central giant cell granuloma, benign jaw tumor, molar, recurrent pericoronitis, multinucleated giant cells. Case report giant cell tumor of the maxilla in an 8 year. Central giant cell granuloma is an uncommon benign proliferative lesion occurring more commonly in the anterior mandible. This lesion occurs most commonly in maxilla and mandible, rare cases have been reported in the bones of skull. Although there is not enough evidence that this lesion promotes. Central giant cell granuloma cgcg is a benign, proliferative, intraosseous and nonodontogenic lesion of unknown etiology.
Because of its overwhelming incidence on the gingiva. These tumors become severely invasive with the stimulus of surgery, resembling malignant. It occurs most commonly on the mandible than in maxilla. A central giant cell granuloma is a type of bone lesion that appears along the jaw. The purpose of this study was to determine the ct characteristics and describe possible mr imaging features of gcg. Central giant cell granuloma cgcg is an uncommon, benign, and. Central giant cell granuloma is a non neoplastic proliferation of unknown etiology. Central giant cell granuloma cgcg is an uncommon benign bony lesion that occurs in the mandible and maxilla. Although central giant cell granulomas cgcgs appear to be benign, their radiographic findings are active. Central giant cell granuloma cgcg, formerly called giant cell reparative granuloma, is a nonneoplastic proliferative lesion of an unknown.
A 9yearold boy was complaining of swelling in the floor of the mouth. It usually presents as a purplishred soft tissue nodule consisting of multinucleated giant cells in. Central giant cell granuloma cgcg, formerly called giant cell reparative granuloma, is a nonneoplastic proliferative lesion of an unknown aetiology. Radiological and epidemiological aspects of central giant. Central giant cell granuloma cgcg is an intraosseous lesion consisting of cellular fibrous tissue that contains multiple foci of hemorrhage, aggregations of multinucleated giant cells. Central giant cell granuloma formerly called as giant cell reparative granuloma is a non neoplastic proliferative lesion of unknown etiology. Giant cell tumour of soft tissue peripheral giant cell granuloma. Central giant cell lesions of the mandible and maxilla. The appearance is generally distinctive with multinucleated giant cells. Aggressive and nonaggressive form, central giant cell granuloma, conventional surgery, differential diagnosis, maxilla, radical surgery. The diagnosis and management of giant cell lesions of the jaws. Recurrent central giant cell granuloma in the mandible. The microscopic appearance of the central giant cell granuloma of the jaws is similar to that of lesions which occur in hyperpituitarism pagets disease hyperparathyroidism cleidocranial dysplasia. Central giant cell granuloma of the jaws regress with calcitonin therapy.
In 1953, jaffe described it as reparative granuloma of jaw bones. Also called giant cell reparative granuloma central if intraosseous. Central giant cell granuloma is a benign condition of the jaws which may present an aggressive behavior. Introduction giant cell reparative granuloma was first described by jaffe in 1953. A central giant cell granuloma in posterior part of.
Full text pimary hyperparathyroidism as central giant. Combination therapies for the treatment of recurrent central giant. Central giant cell granuloma is an uncommon benign intraosseus lesion of jaws. Central giant cell granuloma of the temporal bone author. Giant cell granuloma is an uncommon bony lesion in the head and neck region. Several entities in the jaws can share this histology, including. It may become aggressive leading to expansion and perforation of the cortex. Aggressive central giant cell granuloma of the mandible, a. It is a noncancerous condition that is usually painless, but irritation and open lesions in the mouth can lead.
Central giant cell granuloma in anterior maxilla shwetang goswami1, haripriya2, yashwanth yadav3, ram mohan4 abstract. Between the giant cells are monocluate variants with similar nuclear profiles. Jaffe hl 1953 giantcell reparative granuloma, traumatic bone cyst and. Central giant cell granuloma cgcg is a benign intraosseous lesion that occurs in long. Pdf central giant cell granuloma of the anterior maxilla. Educational video created by unmc college of dentistry class of 2016 dental students. This peripheral giant cell granuloma involved the maxillary gingiva associated with an erupting central incisor of a 6yearold girl. The term giant cell lesion gcl defines a group of intraosseous nonodontogenic benign lesions with multinucleated giant cells gcs. Central giant cell granuloma cgcg is an intraosseous lesion consisting of cellular fibrous tissue that contains multiple foci of hemorrhage, aggregations of. Giant cell granuloma, central multilocular hemangioma, central. Frontal giant cell reparative granuloma invading orbit.
Central giant cell granuloma definition in the cambridge. Fragments consist of cellular proliferation with a conspicuous population of multincelate giant cells. The central giant cell granuloma is a relatively common lesion of the jaws. Pdf central giant cell granuloma cgcg, formerly called giant cell reparative granuloma, is a nonneoplastic proliferative lesion of unknown. A histological comparison of the giant cells in the central giant cell granuloma of the jaws and the giant cell tumor of long bone. Intralesional corticosteroid injection for central giant cell granuloma. Central, giant cell, granuloma, aggressive, jaws introduction central giant cell granuloma cgcg of the jaw is one of the relatively rare pathologic processes and encountered, in less than 7%. Central giantcell granuloma cgcg is a localised benign condition of the jaws. Case report giant cell granuloma of the maxilla usman haider uzbek, iram mushtaq oral and maxillofacial unit, department of dentistry, ayub medical college, abbottabad. Diagnosis of central giant cell granuloma is normally made histologically from an incisional biopsy. Pdf central giant cell granuloma cgcg formerly called giant cell reparative granuloma is a nonneoplastic proliferative lesion of unknown. Central giant cell granuloma cgcg is an intraosseous lesion consisting of cellular fibrous tissue that contains multiple foci of hemorrhage, aggregations of multinucleated giant cells and occasionally. Fibrous dysplasia is a benign fibroosseous lesion arising in an.
An aggressive central giant cell granuloma treated successfully by. The term giant cell reparative granuloma gcrg was first used by jaffe in 1953. Central giant cell granuloma of the mandibular condyle. Central giant cell granuloma cgcg, formerly called giant cell reparative granuloma, is a nonneoplastic proliferative lesion of unknown etiology. The microscopic appearance of the central giant cell. Central giant cell granuloma of the anterior maxilla. Traditional treatment has been local curettage, although aggressive subtypes have a high tendency to recur. Central giant cell lesions granulomas, also known as giant cell reparative cystsgranulomas, occurs.
Giant cell granuloma gcgs was first described by jaffe in 1953 1 as giant cell reparative granuloma, but currently does not refer to him as reparative, because of its locally destructive. Extremely aggressive behavior of central giant cell. Peripheral giant cell granuloma or so called giant cell epulis is the most common oral giant cell lesion. A clinical, radiologic and histopathologic study of 26 cases ooo 2006. It is twice as common in females and is more likely to occur before age 30. Aggressive central giant cell granuloma occurring as peripheral one is a very rare case and the treatment of aggressive central giant cell granuloma with curettage has shown a high recurrence rate within a. Central giant cell granuloma and fibrous dysplasia. Yutaka nemoto, yuichi inoue, takahiko tashiro, tokuro mochizuki, junsuke katsuyama, akira hakuba, and yasuto onoyama subject. Pdf central giant cell granuloma of the posterior maxilla. Central giant cell granuloma cgcg is a benign bone lesion which can be locally aggressive or may be asymptomatic in nature. Peripheral giantcell granuloma pgcg is an oral pathologic condition that appears in the mouth as an overgrowth of tissue due to irritation or trauma. Central giant cell lesions granuloma dr yuranga weerakkody and assoc prof frank gaillard et al.